50-165-9330
DFF45 Mouse anti-Human, Clone: OTI1B10, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-165-9330-Each-of-1 | In Stock | ₹ 58,009.68 |
50-165-9330 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
DFF45
Classification
Monoclonal
Conjugate
Unconjugated
Gene
DFFA
Gene Alias
DFF-45, DFF1, ICAD
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1676
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Clone
OTI1B10
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
O00273
Gene Symbols
DFFA
Immunogen
Recombit protein expressed in E.coli corresponding to amino acids 1-331 of human DFF45
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO ICAD is the inhibitor of caspase-3-activated DNase which is a substrate that controls nuclear apoptosis
- ICAD has two isoforms: a functional isoform of 45kDa, ICAD-L/DNA fragmentation factor (DFF) 45; and a 35kDa isoform, ICAD-S/DFF35
- Although both ICAD-L and ICAD-S can bind and inhibit CAD, only ICAD-L was reported to be functional
- ICAD is cleaved to be inactivated and allow caspase-activated DNase (CAD) to execute nuclear internucleosomal apoptotic DNA fragmentation
- In non-apoptotic cells, CAD is complexed with its inhibitor, ICAD
- The activation of the CAD/ICAD complex occurs through the caspase 3-mediated cleavage of ICAD at residues 117 and 224, which results in three ICAD fragments that are then released from CAD
- In addition to its DNase inhibitory activity, ICAD acts as a CAD specific folding chaperone
- There are recent reports that ICAD is a potential target for restoring a normal apoptotic signal transduction pathway in colon and brain cancer cells
- Two alternatively spliced transcript variants encoding distinct isoforms have been found for the ICAD gene.
Compare Similar Items
Show Difference
Antigen: DFF45
Classification: Monoclonal
Conjugate: Unconjugated
Gene: DFFA
Gene Alias: DFF-45, DFF1, ICAD
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1676
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI1B10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: O00273
Gene Symbols: DFFA
Immunogen: Recombit protein expressed in E.coli corresponding to amino acids 1-331 of human DFF45
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
DFF45
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
DFFA
Gene Alias:
DFF-45, DFF1, ICAD
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1676
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI1B10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
O00273
Gene Symbols:
DFFA
Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 1-331 of human DFF45
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: DFF45
Classification: Monoclonal
Conjugate: Unconjugated
Gene: DFFA
Gene Alias: DFF-45, DFF1, ICAD
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1676
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI3F12
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: O00273
Gene Symbols: DFFA
Immunogen: Full length human recombit protein of human DFFA produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
DFF45
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
DFFA
Gene Alias:
DFF-45, DFF1, ICAD
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1676
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI3F12
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
O00273
Gene Symbols:
DFFA
Immunogen:
Full length human recombit protein of human DFFA produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: IL6
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IL6
Gene Alias: BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3569
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI2G3
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P05231
Gene Symbols: IL6
Immunogen: Recombit protein expressed in E.coli corresponding to amino acids 29-212 of human IL-6
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Antigen:
IL6
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IL6
Gene Alias:
BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3569
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI2G3
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P05231
Gene Symbols:
IL6
Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 29-212 of human IL-6
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Antigen: SERPINA1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: SERPINA1
Gene Alias: A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, nNIF
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5265
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI3C5
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P01009
Gene Symbols: SERPINA1
Immunogen: Human recombit protein fragment corresponding to amino acids 26-418 of human A1AT produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
SERPINA1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
SERPINA1
Gene Alias:
A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, nNIF
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5265
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI3C5
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P01009
Gene Symbols:
SERPINA1
Immunogen:
Human recombit protein fragment corresponding to amino acids 26-418 of human A1AT produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b