50-165-9481

CD2 Mouse anti-Human, Clone: OTI4E4, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-165-9481-Each-of-1 In Stock ₹ 58,009.68

50-165-9481 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CD2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CD2

Gene Alias

LFA-2, SRBC, T11

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

914

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Western Blot

Clone

OTI4E4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P06729

Gene Symbols

CD2

Immunogen

Full-length protein expressed in 293T cell transfected with human CD2 expression vector

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction betwee CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

OriGene

50-165-9481

--


Antigen:
CD2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD2

Gene Alias:
LFA-2, SRBC, T11

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Clone:
OTI4E4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
Full-length protein expressed in 293T cell transfected with human CD2 expression vector

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-165-9482

--


Antigen:
CHEK2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CHEK2

Gene Alias:
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11200, 114212, 486338

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI2F4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O96017

Gene Symbols:
CHEK2

Immunogen:
Full length human recombit protein of human CHEK2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Rat

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-165-9484

--


Antigen:
SSB

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SSB

Gene Alias:
LARP3, La, La/SSB

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
478787, 6741

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
OTI9D6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P05455

Gene Symbols:
SSB

Immunogen:
Full-length protein expressed in 293T cell transfected with human SSB expression vector

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG3

Img

OriGene

50-165-9487

--


Antigen:
SSB

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SSB

Gene Alias:
LARP3, La, La/SSB

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
478787, 6741

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
OTI3H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P05455

Gene Symbols:
SSB

Immunogen:
Full-length protein expressed in 293T cell transfected with human SSB expression vector

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a