50-165-9604

BUB1B Mouse anti-Human, Clone: OTI3C7, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-165-9604-Each-of-1 In Stock ₹ 58,009.68

50-165-9604 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

BUB1B

Classification

Monoclonal

Conjugate

Unconjugated

Gene

BUB1B

Gene Alias

BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

701

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3C7

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O60566

Gene Symbols

BUB1B

Immunogen

Full-length protein expressed in 293T cell transfected with human BUB1B expression vector

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO BUBR1 is a member of the Ser/Thr protein kinase family
  • It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
  • Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to maligt transformations
  • Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
  • They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
  • hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
  • BUBR1 has been detected in human cancers
  • It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.

Compare Similar Items

Show Difference

Img

OriGene

50-165-9604

--


Antigen:
BUB1B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BUB1B

Gene Alias:
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
701

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3C7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O60566

Gene Symbols:
BUB1B

Immunogen:
Full-length protein expressed in 293T cell transfected with human BUB1B expression vector

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-165-9605

--


Antigen:
BUB1B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BUB1B

Gene Alias:
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
701

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI10B7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O60566

Gene Symbols:
BUB1B

Immunogen:
Full-length protein expressed in 293T cell transfected with human BUB1B expression vector

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-165-9606

--


Antigen:
NTRK3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NTRK3

Gene Alias:
GP145-TrkC, TRKC, gp145(trkC)

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4916

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI24B3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q16288

Gene Symbols:
NTRK3

Immunogen:
Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-165-9608

--


Antigen:
NTRK3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NTRK3

Gene Alias:
GP145-TrkC, TRKC, gp145(trkC)

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4916

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4E10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q16288

Gene Symbols:
NTRK3

Immunogen:
Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1