50-165-97
T-bet Monoclonal Antibody (eBio4B10 (4B10)), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-165-97-Each-of-1 | In Stock | ₹ 15,486.36 |
50-165-97 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,486.36
GST (18%): ₹ 2,787.545
Total Price: ₹ 18,273.905
Antigen
T-bet
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9JKD8, Q9UL17
Gene Symbols
Tbx21
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
30009, 57765, 694044
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio4B10 (4B10)
Conjugate
eFluor 660
Gene
Tbx21
Gene Alias
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species
Mouse
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The eBio4B10 monoclonal antibody reacts with mouse and human T-bet
- T-bet is a Th1-specific T-box transcription factor critical to the development of the Th1 CD4+ T cell lineage
- This is known based on the observations that T-Bet deficient mice have impaired Th1 cell development, and that ectopic expression of T-Bet results in development skewed to the Th1 lineage
- T-Bet expression is induced by the Th1 cytokine IFN gamma, and T-Bet also regulates the expression of IFN gamma, likely, at least in part, through the modification of DNA accessibility and histone remodeling
- In addition to IFN gamma, T-Bet is also known to regulate the expression of IL-12R beta and IL-2
- Moreover, T-Bet plays a role in class-switch recombination in B-cells
- Applications Reported: This eBio4B10 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This eBio4B10 antibody has been tested by intracellular staining and flow cytometric analysis of normal human peripheral blood cells
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain
- It controls the expression of the TH1 cytokine, interferon-gamma
- Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development
- T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17
- T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression
- Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.
Compare Similar Items
Show Difference
Antigen: T-bet
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9JKD8, Q9UL17
Gene Symbols: Tbx21
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 30009, 57765, 694044
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio4B10 (4B10)
Conjugate: eFluor 660
Gene: Tbx21
Gene Alias: HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species: Mouse
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
T-bet
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9JKD8, Q9UL17
Gene Symbols:
Tbx21
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
30009, 57765, 694044
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio4B10 (4B10)
Conjugate:
eFluor 660
Gene:
Tbx21
Gene Alias:
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species:
Mouse
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: SLC7A8
Classification: Monoclonal
Concentration: __
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q9UHI5
Gene Symbols: SLC7A8
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23428
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Clone: OTI4H10
Conjugate: Unconjugated
Gene: SLC7A8
Gene Alias: ATP3
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
SLC7A8
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q9UHI5
Gene Symbols:
SLC7A8
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23428
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Clone:
OTI4H10
Conjugate:
Unconjugated
Gene:
SLC7A8
Gene Alias:
ATP3
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: LTA4H
Classification: Monoclonal
Concentration: __
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P09960
Gene Symbols: LTA4H
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4048
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI9C5
Conjugate: Unconjugated
Gene: LTA4H
Gene Alias: leukotriene A4 hydrolase
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
LTA4H
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P09960
Gene Symbols:
LTA4H
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4048
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI9C5
Conjugate:
Unconjugated
Gene:
LTA4H
Gene Alias:
leukotriene A4 hydrolase
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: PRKAR1A
Classification: Monoclonal
Concentration: __
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P10644
Gene Symbols: PRKAR1A
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5573
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI6C7
Conjugate: Unconjugated
Gene: PRKAR1A
Gene Alias: ACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, TSE1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
PRKAR1A
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P10644
Gene Symbols:
PRKAR1A
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5573
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI6C7
Conjugate:
Unconjugated
Gene:
PRKAR1A
Gene Alias:
ACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, TSE1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1