50-166-0141

SHC1 Mouse anti-Human, Clone: OTI3H1, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-0141-Each-of-1 In Stock ₹ 58,009.68

50-166-0141 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

SHC1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

SHC1

Gene Alias

SHC, SHCA

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6464

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone

OTI3H1

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P29353

Gene Symbols

SHC1

Immunogen

Full length human recombit protein of human SHC1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Signaling adapter that couples activated growth factor receptors to signaling pathways
  • Participates in a signaling cascade initiated by activated KIT and KITLG/SCF
  • Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals
  • Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems
  • Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span
  • Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis
  • The expression of isoform p66Shc has been correlated with life span
  • Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.

Compare Similar Items

Show Difference

Img

OriGene

50-166-0141

--


Antigen:
SHC1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SHC1

Gene Alias:
SHC, SHCA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6464

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI3H1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P29353

Gene Symbols:
SHC1

Immunogen:
Full length human recombit protein of human SHC1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-0142

--


Antigen:
PRKAR2A

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PRKAR2A

Gene Alias:
PKR2, PRKAR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5576

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1G7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P13861

Gene Symbols:
PRKAR2A

Immunogen:
Full length human recombit protein of human PRKAR2A produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-0144

--


Antigen:
PRKAR2A

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PRKAR2A

Gene Alias:
PKR2, PRKAR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5576

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P13861

Gene Symbols:
PRKAR2A

Immunogen:
Full length human recombit protein of human PRKAR2A produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-0145

--


Antigen:
VAT1L

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VAT1L

Gene Alias:
vesicle amine transport 1 like

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57687

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1H3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9HCJ6

Gene Symbols:
VAT1L

Immunogen:
Full length human recombit protein of human VAT1L produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1