50-166-0711

SMAD2 Mouse anti-Human, Clone: OTI2C10, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-0711-Each-of-1 In Stock ₹ 58,009.68

50-166-0711 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

SMAD2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

SMAD2

Gene Alias

JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4087

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone

OTI2C10

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q15796

Gene Symbols

SMAD2

Immunogen

Full length human recombit protein of human SMAD2 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
  • SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
  • Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
  • In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
  • The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
  • The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
  • SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
  • Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.

Compare Similar Items

Show Difference

Img

OriGene

50-166-0711

--


Antigen:
SMAD2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4087

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI2C10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q15796

Gene Symbols:
SMAD2

Immunogen:
Full length human recombit protein of human SMAD2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-0712

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Antigen:
GGPS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GGPS1

Gene Alias:
GGPPS, GGPPS1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9453

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2E7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95749

Gene Symbols:
GGPS1

Immunogen:
Full length human recombit protein of human GGPS1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-0713

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Antigen:
GGPS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GGPS1

Gene Alias:
GGPPS, GGPPS1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9453

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1C6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95749

Gene Symbols:
GGPS1

Immunogen:
Full length human recombit protein of human GGPS1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-0714

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Antigen:
GGPS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GGPS1

Gene Alias:
GGPPS, GGPPS1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9453

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3F9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95749

Gene Symbols:
GGPS1

Immunogen:
Full length human recombit protein of human GGPS1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1