50-166-1252

Beta-catenin Mouse anti-Canine, Human, Rat, Clone: OTI9H2, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-1252-Each-of-1 In Stock ₹ 58,009.68

50-166-1252 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

Beta-catenin

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CTNNB1

Gene Alias

CTNNB, EVR7, MRD19, armadillo

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1499, 477032, 84353

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI9H2

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

B6V8E6, P35222, Q9WU82

Gene Symbols

CTNNB1

Immunogen

Full length human recombit protein of human CTNNB1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Rat

Product Type

Antibody

Isotype

IgG2b

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
  • AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
  • Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
  • Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
  • The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
  • Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
  • A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
  • In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
  • The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.

Compare Similar Items

Show Difference

Img

OriGene

50-166-1252

--


Antigen:
Beta-catenin

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
CTNNB, EVR7, MRD19, armadillo

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1499, 477032, 84353

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI9H2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
B6V8E6, P35222, Q9WU82

Gene Symbols:
CTNNB1

Immunogen:
Full length human recombit protein of human CTNNB1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Rat

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-1253

--


Antigen:
NUDT6

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NUDT6

Gene Alias:
ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI10A9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P53370

Gene Symbols:
NUDT6

Immunogen:
Full length human recombit protein of human NUDT6 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-1254

--


Antigen:
NUDT6

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NUDT6

Gene Alias:
ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI9D12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P53370

Gene Symbols:
NUDT6

Immunogen:
Full length human recombit protein of human NUDT6 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-1257

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Antigen:
ZFAND2B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ZFAND2B

Gene Alias:
AIRAPL

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
130617

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI1D5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8WV99

Gene Symbols:
ZFAND2B

Immunogen:
Full length human recombit protein of human ZFAND2B produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1