50-166-1761

LGR5 Mouse anti-Human, Clone: OTI2H7, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-1761-Each-of-1 In Stock ₹ 58,009.68

50-166-1761 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

LGR5

Classification

Monoclonal

Conjugate

Unconjugated

Gene

LGR5

Gene Alias

FEX, GPR49, GPR67, GRP49, HG38

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8549

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2H7

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O75473

Gene Symbols

LGR5

Immunogen

Human recombit protein fragment corresponding to amino acids 250-550 of human LGR5 produced in 293T Cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord
  • ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This ""turn-off"" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

OriGene

50-166-1761

--


Antigen:
LGR5

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LGR5

Gene Alias:
FEX, GPR49, GPR67, GRP49, HG38

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2H7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O75473

Gene Symbols:
LGR5

Immunogen:
Human recombit protein fragment corresponding to amino acids 250-550 of human LGR5 produced in 293T Cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-1764

--


Antigen:
LGR5

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LGR5

Gene Alias:
FEX, GPR49, GPR67, GRP49, HG38

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI7H7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O75473

Gene Symbols:
LGR5

Immunogen:
Human recombit protein fragment corresponding to amino acids 250-550 of human LGR5 produced in 293T Cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-1765

--


Antigen:
UBOX5

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
UBOX5

Gene Alias:
RNF37, UBCE7IP5, UIP5, hUIP5

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22888

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Clone:
OTI5G9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O94941

Gene Symbols:
UBOX5

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-130 and 419-487 of human UBOX5 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-1767

--


Antigen:
FGF21

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FGF21

Gene Alias:
fibroblast growth factor 21

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26291

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI2E2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9NSA1

Gene Symbols:
FGF21

Immunogen:
Human recombit protein fragment corresponding to amino acids 29-209 of human FGF21 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1