50-166-2036
DOK2 Mouse anti-Human, Clone: OTI2A3, lyophilized, TrueMAB™
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-2036-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-2036 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
DOK2
Classification
Monoclonal
Conjugate
Unconjugated
Gene
DOK2
Gene Alias
p56DOK, p56dok-2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9046
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone
OTI2A3
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
O60496
Gene Symbols
DOK2
Immunogen
Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO Docking proteins interact with receptor tyrosine kinases and mediate particular biological responses using signal transduction
- Dok-2 acts as a multiple docking protein downstream of receptor or non-receptor tyrosine kinases
- By this mechanism it acts to negatively regulate signal transduction and cell proliferation controlled by cytokines in a feedback loop
- Dok-2 is highly expressed in cells and tissues of hematopoietic origin as well as in lung
- Expression of bcr/abl induces additional tyrosine phosphorylation of the Dok1 and Dok2 proteins and their association with Ras-GAP
- Thus, it is suspected that DOK association regulates GAP activity toward Ras and that the Dok proteins serve as mediators of bcr-abl signaling
- The role of Dok proteins in bcr-abl regulation may also be implicated in chronic myelogenous leukemia (CML), which is characterized by a Philadelphia chromosome translocation t(9;22)
- Such a mutation would result in a p210-bcr/abl chimeric protein-tyrosine kinase which has been found in many CML cases.
Compare Similar Items
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Antigen: DOK2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56DOK, p56dok-2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9046
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI2A3
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: O60496
Gene Symbols: DOK2
Immunogen: Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
DOK2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56DOK, p56dok-2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9046
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI2A3
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
O60496
Gene Symbols:
DOK2
Immunogen:
Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: DOK2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56DOK, p56dok-2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9046
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI1G9
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: O60496
Gene Symbols: DOK2
Immunogen: Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
DOK2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56DOK, p56dok-2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9046
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI1G9
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
O60496
Gene Symbols:
DOK2
Immunogen:
Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: AK4
Classification: Monoclonal
Conjugate: Unconjugated
Gene: AK4
Gene Alias: AK 4, AK3, AK3L1, AK3L2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 205, 489554
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2B12
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P27144
Gene Symbols: AK4
Immunogen: Full length human recombit protein of human AK4 produced in HEK293 cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG1
Antigen:
AK4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
AK4
Gene Alias:
AK 4, AK3, AK3L1, AK3L2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
205, 489554
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2B12
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P27144
Gene Symbols:
AK4
Immunogen:
Full length human recombit protein of human AK4 produced in HEK293 cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: PTPN1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: PTPN1
Gene Alias: PTP1B
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 477263, 5770
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1D10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P18031
Gene Symbols: PTPN1
Immunogen: Full length human recombit protein of human PTPN1 produced in HEK293 cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
PTPN1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
PTPN1
Gene Alias:
PTP1B
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
477263, 5770
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1D10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P18031
Gene Symbols:
PTPN1
Immunogen:
Full length human recombit protein of human PTPN1 produced in HEK293 cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG2a