50-166-2140
ERBB2 Mouse anti-Human, Clone: OTI4F10, lyophilized, TrueMAB™
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-2140-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-2140 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
ERBB2
Classification
Monoclonal
Conjugate
Unconjugated
Gene
ERBB2
Gene Alias
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2064
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI4F10
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P04626
Gene Symbols
ERBB2
Immunogen
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
- ErbB2 has no ligand binding domain of its own and cannot bind growth factors
- However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
- Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
- Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
- In humans, the gene encoding ERBB2 is present on chromosome 17
- Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.
Compare Similar Items
Show Difference
Antigen: ERBB2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4F10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
ERBB2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4F10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: ASNS
Classification: Monoclonal
Conjugate: Unconjugated
Gene: ASNS
Gene Alias: ASNSD, TS11
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 440
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI1B2
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P08243
Gene Symbols: ASNS
Immunogen: Full length human recombit protein of human ASNS produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ASNS
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ASNS
Gene Alias:
ASNSD, TS11
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
440
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI1B2
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P08243
Gene Symbols:
ASNS
Immunogen:
Full length human recombit protein of human ASNS produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: PDE4B
Classification: Monoclonal
Conjugate: Unconjugated
Gene: PDE4B
Gene Alias: DPDE4, PDEIVB
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5142
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry, Western Blot
Clone: OTI2B10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q07343
Gene Symbols: PDE4B
Immunogen: Full length human recombit protein of human PDE4B produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
PDE4B
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
PDE4B
Gene Alias:
DPDE4, PDEIVB
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5142
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry, Western Blot
Clone:
OTI2B10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q07343
Gene Symbols:
PDE4B
Immunogen:
Full length human recombit protein of human PDE4B produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: PMVK
Classification: Monoclonal
Conjugate: Unconjugated
Gene: PMVK
Gene Alias: HUMPMKI, PMK, PMKA, PMKASE, POROK1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10654
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI1C12
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q15126
Gene Symbols: PMVK
Immunogen: Full length human recombit protein of human PMVK produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
PMVK
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
PMVK
Gene Alias:
HUMPMKI, PMK, PMKA, PMKASE, POROK1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10654
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI1C12
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q15126
Gene Symbols:
PMVK
Immunogen:
Full length human recombit protein of human PMVK produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a