50-166-2201

WWTR1 Mouse anti-Human, Clone: OTI1H9, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-2201-Each-of-1 In Stock ₹ 58,009.68

50-166-2201 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

WWTR1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

WWTR1

Gene Alias

TAZ

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25937

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1H9

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q9GZV5

Gene Symbols

WWTR1

Immunogen

Full length human recombit protein of human WWTR1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO WW domain-containing transcription regulator protein 1 (WWTR1) is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor supression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1
  • In turn, MOB1 phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation
  • WWTR1 regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex
  • WWTR1 also regulates embryonic stem-cell self-renewal and promotes cell proliferation and epithelial-mesenchymal transition.

Compare Similar Items

Show Difference

Img

OriGene

50-166-2201

--


Antigen:
WWTR1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
WWTR1

Gene Alias:
TAZ

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25937

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9GZV5

Gene Symbols:
WWTR1

Immunogen:
Full length human recombit protein of human WWTR1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-2202

--


Antigen:
PPARA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PPARA

Gene Alias:
NR1C1, PPAR, PPARalpha, hPPAR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5465

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI3G3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q07869

Gene Symbols:
PPARA

Immunogen:
Human recombit protein fragment corresponding to amino acids 145-420 of human PPARA produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-2203

--


Antigen:
PPARA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PPARA

Gene Alias:
NR1C1, PPAR, PPARalpha, hPPAR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19013, 5465

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI1E8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P23204, Q07869

Gene Symbols:
PPARA

Immunogen:
Human recombit protein fragment corresponding to amino acids 145-420 of human PPARA produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-2204

--


Antigen:
PPARA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PPARA

Gene Alias:
NR1C1, PPAR, PPARalpha, hPPAR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5465

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI1E11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q07869

Gene Symbols:
PPARA

Immunogen:
Human recombit protein fragment corresponding to amino acids 145-420 of human PPARA produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1