50-166-2542

USP7 Mouse anti-Human, Clone: OTI1F12, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-2542-Each-of-1 In Stock ₹ 60,342.00

50-166-2542 - Each of 1

₹ 60,342.00

In Stock

Quantity

1

Base Price: ₹ 60,342.00

GST (18%): ₹ 10,861.56

Total Price: ₹ 71,203.56

Antigen

USP7

Classification

Monoclonal

Conjugate

Unconjugated

Gene

USP7

Gene Alias

HAUSP, TEF1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7874

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1F12

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q93009

Gene Symbols

USP7

Immunogen

Full length human recombit protein of human USP7 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
  • Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP acitivity generally stabilizes its substrate proteins
  • HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53.Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
  • Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
  • Another important role of HAUSP function involves the oncogenic stabilization of p53
  • Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
  • An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.

Compare Similar Items

Show Difference

Img

OriGene

50-166-2542

--


Antigen:
USP7

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
USP7

Gene Alias:
HAUSP, TEF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7874

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1F12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q93009

Gene Symbols:
USP7

Immunogen:
Full length human recombit protein of human USP7 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-2544

--


Antigen:
RGS16

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RGS16

Gene Alias:
A28-RGS14, A28-RGS14P, RGS-R

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6004

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3F3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O15492

Gene Symbols:
RGS16

Immunogen:
Full length human recombit protein of human produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-2545

--


Antigen:
RGS16

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RGS16

Gene Alias:
A28-RGS14, A28-RGS14P, RGS-R

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6004

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1F3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O15492

Gene Symbols:
RGS16

Immunogen:
Full length human recombit protein of human RGS16 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-2547

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Antigen:
SDS

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SDS

Gene Alias:
SDH

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10993

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Clone:
OTI4E1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P20132

Gene Symbols:
SDS

Immunogen:
Full length human recombit protein of human SDS produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1