50-166-4026
GZMB Mouse anti-Human, Clone: OTI4E6, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-4026-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-4026 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
GZMB
Classification
Monoclonal
Conjugate
Unconjugated
Gene
GZMB
Gene Alias
C11, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3002
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI4E6
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P10144
Gene Symbols
GZMB
Immunogen
Human recombit protein fragment corresponding to amino acids 21-247 of human GZMB produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells
- Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells
- Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells
- The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Granzyme B during cytotoxic T cell-induced apoptosis
- Granzyme B enters target cells to cleave caspase-3 and initiate the caspase cascade leading to DNA fragmentation and apoptosis
- Granzyme B can also act through a mitochondrial apoptosis pathway by cleaving the Bid protein
- Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells
- A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified.
Compare Similar Items
Show Difference
Antigen: GZMB
Classification: Monoclonal
Conjugate: Unconjugated
Gene: GZMB
Gene Alias: C11, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3002
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4E6
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P10144
Gene Symbols: GZMB
Immunogen: Human recombit protein fragment corresponding to amino acids 21-247 of human GZMB produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
GZMB
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
GZMB
Gene Alias:
C11, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3002
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4E6
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P10144
Gene Symbols:
GZMB
Immunogen:
Human recombit protein fragment corresponding to amino acids 21-247 of human GZMB produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: SESTD1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: SESTD1
Gene Alias: SOLO
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 228071, 91404
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2E7
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q80UK0, Q86VW0
Gene Symbols: Sestd1
Immunogen: Full length human recombit protein of human SESTD1 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
SESTD1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
SESTD1
Gene Alias:
SOLO
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
228071, 91404
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2E7
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q80UK0, Q86VW0
Gene Symbols:
Sestd1
Immunogen:
Full length human recombit protein of human SESTD1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: SESTD1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: SESTD1
Gene Alias: SOLO
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 228071, 91404
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4B10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q80UK0, Q86VW0
Gene Symbols: SESTD1
Immunogen: Full length human recombit protein of human SESTD1 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
SESTD1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
SESTD1
Gene Alias:
SOLO
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
228071, 91404
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4B10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q80UK0, Q86VW0
Gene Symbols:
SESTD1
Immunogen:
Full length human recombit protein of human SESTD1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: LZIC
Classification: Monoclonal
Conjugate: Unconjugated
Gene: LZIC
Gene Alias: leucine zipper and CTNNBIP1 domain containing
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84328
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI2D3
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q8WZA0
Gene Symbols: LZIC
Immunogen: Human recombit protein fragment corresponding to amino acids 1-190 of human LZIC produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
LZIC
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
LZIC
Gene Alias:
leucine zipper and CTNNBIP1 domain containing
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84328
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI2D3
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q8WZA0
Gene Symbols:
LZIC
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-190 of human LZIC produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a