50-166-4230

DDX58 Mouse anti-Human, Clone: OTI8D2, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-4230-Each-of-1 In Stock ₹ 58,009.68

50-166-4230 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

DDX58

Classification

Monoclonal

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

RIG-I, RIGI, RLR-1, SGMRT2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI8D2

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

Full length human recombit protein of human DDX58 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5′-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and ultimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

Show Difference

Img

OriGene

50-166-4230

--


Antigen:
DDX58

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
RIG-I, RIGI, RLR-1, SGMRT2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8D2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
Full length human recombit protein of human DDX58 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-4231

--


Antigen:
NCAM1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NCAM1

Gene Alias:
CD56, MSK39, NCAM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17967, 24586, 4684, 479435

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1G4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P13591, P13595, P13596

Gene Symbols:
NCAM1

Immunogen:
Human recombit protein fragment corresponding to amino acids 20-718 of human NCAM1 produced in HEK293T cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-4232

--


Antigen:
EGFR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
ERBB, ERBB1, HER1, NISBD2, PIG61, mENA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1956

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI2G8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P00533

Gene Symbols:
EGFR

Immunogen:
Full length human recombit protein of human EGFR produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-4233

--


Antigen:
VHL

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VHL

Gene Alias:
HRCA1, RCA1, VHL1, pVHL

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7428

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P40337

Gene Symbols:
VHL

Immunogen:
Full length human recombit protein of human VHL produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b