50-166-4394

PMS2 Mouse anti-Human, Clone: OTI2G5, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-4394-Each-of-1 In Stock ₹ 58,009.68

50-166-4394 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

PMS2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PMS2

Gene Alias

HNPCC4, MLH4, PMS2CL, PMSL2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5395

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2G5

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P54278

Gene Symbols

PMS2

Immunogen

Full length human recombit protein of human PMS2 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Mismatch DNA repair in bacteria is carried out by the MutL, MutH, and MutS proteins
  • The MutS protein initially binds to mismatched DNA
  • This is followed by binding of the MutH endonuclease and MutL to form a complex that carries out excision repair
  • The hMSH2 gene specifies a MutS homologue and hMLH1, hPMS1, and hPMS2 encode MutL homologs
  • Mutations in these genes are associated with hereditary nonpolyposis colon cancer (HNPCC), one of the most common hereditary diseases in man
  • As with the bacterial system, HNPCC is characterized by frequent microsatellite mutations that arise by somatic mutation due to a replication error (RER+) phenotype
  • Both hPMS1 and hPMS2 are mutated in the germline of HNPCC patients
  • Although the exact function of MutL and its homologs has yet to be determined, it is known that a complex of PMS2 and MLH1 (MutLa) from HeLa cells can complement a deficiency of MLH1 in hypermutable H6 colorectal tumor cells.

Compare Similar Items

Show Difference

Img

OriGene

50-166-4394

--


Antigen:
PMS2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PMS2

Gene Alias:
HNPCC4, MLH4, PMS2CL, PMSL2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5395

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2G5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P54278

Gene Symbols:
PMS2

Immunogen:
Full length human recombit protein of human PMS2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-4395

--


Antigen:
EPCAM

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
EPCAM

Gene Alias:
DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI3B2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P16422

Gene Symbols:
EPCAM

Immunogen:
Full length human recombit protein of human EPCAM produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-4396

--


Antigen:
PMS2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PMS2

Gene Alias:
HNPCC4, MLH4, PMS2CL, PMSL2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5395

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4B7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P54278

Gene Symbols:
PMS2

Immunogen:
Full length human recombit protein of human PMS2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-4397

--


Antigen:
TUBB2B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TUBB2B

Gene Alias:
CDCBM7, PMGYSA, bA506K6.1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
347733

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8F12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9BVA1

Gene Symbols:
TUBB2B

Immunogen:
Full length human recombit protein of human TUBB2B produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a