50-166-5021

RIPK1 Mouse anti-Canine, Human, Clone: OTI1A7, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-5021-Each-of-1 In Stock ₹ 58,009.68

50-166-5021 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

RIPK1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

RIPK1

Gene Alias

RIP, RIP-1, RIP1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

102152063, 8737

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI1A7

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q13546

Gene Symbols

RIPK1

Immunogen

Human recombit protein fragment corresponding to amino acids 133-422 of human RIPK1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage
  • Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor
  • Phosphorylates DAB2IP at ′Ser-728′ in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade
  • Ubiquitination by TRAF2 via ′Lys-63′-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules
  • Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation
  • Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death
  • RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.

Compare Similar Items

Show Difference

Img

OriGene

50-166-5021

--


Antigen:
RIPK1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RIPK1

Gene Alias:
RIP, RIP-1, RIP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
102152063, 8737

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1A7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q13546

Gene Symbols:
RIPK1

Immunogen:
Human recombit protein fragment corresponding to amino acids 133-422 of human RIPK1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-5022

--


Antigen:
APEX1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
APEX1

Gene Alias:
APE, APE1, APEN, APEX, APX, HAP1, REF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
328, 482558

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P27695

Gene Symbols:
APEX1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-242 of human APEX1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-5023

--


Antigen:
APEX1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
APEX1

Gene Alias:
APE, APE1, APEN, APEX, APX, HAP1, REF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
328

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2A4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P27695

Gene Symbols:
APEX1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-242 of human APEX1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-5026

--


Antigen:
F13A1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
F13A1

Gene Alias:
F13A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1C9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P00488

Gene Symbols:
F13A1

Immunogen:
Full length human recombit protein of human F13A1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1