50-166-5155

CD20 (MS4A1) Mouse anti-Human, Clone: OTI11F7, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-5155-Each-of-1 In Stock ₹ 58,009.68

50-166-5155 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CD20 (MS4A1)

Classification

Monoclonal

Conjugate

Unconjugated

Gene

MS4A1

Gene Alias

B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

931

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI11F7

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P11836

Gene Symbols

MS4A1

Immunogen

Full length human recombit protein of human MS4A1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
  • CD20 is expressed on mature and most maligt B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
  • CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
  • CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
  • After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
  • CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell maligcies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
  • Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.

Compare Similar Items

Show Difference

Img

OriGene

50-166-5155

--


Antigen:
CD20 (MS4A1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MS4A1

Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
931

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI11F7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P11836

Gene Symbols:
MS4A1

Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-5156

--


Antigen:
CD20 (MS4A1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MS4A1

Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
931

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P11836

Gene Symbols:
MS4A1

Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-5157

--


Antigen:
ZSCAN4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ZSCAN4

Gene Alias:
ZNF494

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
201516

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8NAM6

Gene Symbols:
ZSCAN4

Immunogen:
Human recombit protein fragment corresponding to amino acids 164-433 of human ZSCAN4 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-5158

--


Antigen:
ZSCAN4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ZSCAN4

Gene Alias:
ZNF494

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
201516

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1A6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8NAM6

Gene Symbols:
ZSCAN4

Immunogen:
Human recombit protein fragment corresponding to amino acids 164-433 of human ZSCAN4 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1