50-166-5262

CD2 Mouse anti-Human, Clone: OTI2C3, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-5262-Each-of-1 In Stock ₹ 58,009.68

50-166-5262 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CD2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CD2

Gene Alias

LFA-2, SRBC, T11

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

914

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI2C3

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P06729

Gene Symbols

CD2

Immunogen

Full length human recombit protein of human CD2 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Related Products

Img

OriGene

50-166-5249

--

Img

OriGene

50-166-5248

--

Img

OriGene

50-166-5178

--

Img

OriGene

50-166-5176

--

Img

OriGene

50-166-5177

--

Img

OriGene

50-166-5149

--

Img

OriGene

50-166-5166

--

Img

OriGene

50-166-5168

--

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction betwee CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

OriGene

50-166-5262

--


Antigen:
CD2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD2

Gene Alias:
LFA-2, SRBC, T11

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2C3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
Full length human recombit protein of human CD2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-5263

--


Antigen:
SERBP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SERBP1

Gene Alias:
CGI-55, CHD3IP, HABP4L, PAI-RBP1, PAIRBP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
246303, 26135, 479535, 66870

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2E11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q6AXS5, Q8NC51, Q9CY58

Gene Symbols:
Serbp1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-262 of human SERBP1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-5267

--


Antigen:
ALK

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
CD246, NBLST3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6G8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UM73

Gene Symbols:
ALK

Immunogen:
Human recombit protein fragment corresponding to amino acids 1060-1620 of human ALK produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-5268

--


Antigen:
ALK

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
CD246, NBLST3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5C8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UM73

Gene Symbols:
ALK

Immunogen:
Full length human recombit protein of human ALK produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b