50-166-5436

ESR2 Mouse anti-Human, Clone: OTI3E4, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-5436-Each-of-1 In Stock ₹ 58,009.68

50-166-5436 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

ESR2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ESR2

Gene Alias

ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2100

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI3E4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q92731

Gene Symbols

ESR2

Immunogen

Human recombit protein fragment corresponding to amino acids 1-260 of human ESR2 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described
  • Human ER beta was initially cloned and characterized from testis
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha
  • Some ER beta isoforms domitly inhibit the activity of estrogen receptor alpha in reproductive tissues
  • ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease.

Compare Similar Items

Show Difference

Img

OriGene

50-166-5436

--


Antigen:
ESR2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ESR2

Gene Alias:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2100

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3E4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q92731

Gene Symbols:
ESR2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-260 of human ESR2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-5437

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Antigen:
ALK

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
CD246, NBLST3

Host Species:
Rat

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1C2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UM73

Gene Symbols:
ALK

Immunogen:
Human recombit protein fragment corresponding to amino acids 1060-1620 of human ALK produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-5438

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Antigen:
FGFR3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FGFR3

Gene Alias:
ACH, CD333, CEK2, HSFGFR3EX, JTK4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2261

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1B10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P22607

Gene Symbols:
FGFR3

Immunogen:
Human recombit protein fragment corresponding to amino acids 23-375 of human FGFR3 produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-5439

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Antigen:
S100A1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
S100A1

Gene Alias:
S100, S100-alpha, S100A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6271

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI9F3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P23297

Gene Symbols:
S100A1

Immunogen:
Full length human recombit protein of human S100A1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1