50-166-6075

BRCA1 Mouse anti-Human, Clone: OTI5D10, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-6075-Each-of-1 In Stock ₹ 58,009.68

50-166-6075 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

BRCA1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

BRCA1

Gene Alias

BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

672

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI5D10

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P38398

Gene Symbols

BRCA1

Immunogen

Human recombit protein fragment corresponding to amino acids 1151-1473 of human BRCA1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor in combination with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC (for BRCA1 associated genome surveillance complex)
  • BRCA1 associates with RNA polymerase II, and through the C terminal domain, also interacts with histone deacetylase complex
  • The BRCA1 protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in the BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified.

Compare Similar Items

Show Difference

Img

OriGene

50-166-6075

--


Antigen:
BRCA1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BRCA1

Gene Alias:
BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5D10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1151-1473 of human BRCA1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6077

--


Antigen:
PARN

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PARN

Gene Alias:
DAN, DKCB6, PFBMFT4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5073

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1G5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95453

Gene Symbols:
PARN

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-266 of human PARN produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-6080

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Antigen:
PARN

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PARN

Gene Alias:
DAN, DKCB6, PFBMFT4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5073

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3G9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95453

Gene Symbols:
PARN

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-266 of human PARN produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6081

--


Antigen:
PARN

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PARN

Gene Alias:
DAN, DKCB6, PFBMFT4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5073

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4C9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95453

Gene Symbols:
PARN

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-266 of human PARN produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a