50-166-6286
BCL2 Mouse anti-Human, Clone: OTI2E5, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-6286-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-6286 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
BCL2
Classification
Monoclonal
Conjugate
Unconjugated
Gene
BCL2
Gene Alias
Bcl-2, PPP1R50
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
596
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2E5
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P10415
Gene Symbols
BCL2
Immunogen
Full length human recombit protein of human BCL2 produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Compare Similar Items
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Antigen: BCL2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: BCL2
Gene Alias: Bcl-2, PPP1R50
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 596
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2E5
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P10415
Gene Symbols: BCL2
Immunogen: Full length human recombit protein of human BCL2 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
BCL2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
BCL2
Gene Alias:
Bcl-2, PPP1R50
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
596
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2E5
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P10415
Gene Symbols:
BCL2
Immunogen:
Full length human recombit protein of human BCL2 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: KRT24
Classification: Monoclonal
Conjugate: Unconjugated
Gene: KRT24
Gene Alias: K24, KA24
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 192666
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI3A2
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q2M2I5
Gene Symbols: KRT24
Immunogen: Human recombit protein fragment corresponding to amino acids 139-397 of human KRT24 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
KRT24
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
KRT24
Gene Alias:
K24, KA24
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
192666
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI3A2
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q2M2I5
Gene Symbols:
KRT24
Immunogen:
Human recombit protein fragment corresponding to amino acids 139-397 of human KRT24 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: EZH2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: EZH2
Gene Alias: ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2146
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI10B10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q15910
Gene Symbols: EZH2
Immunogen: Human recombit protein fragment corresponding to amino acids 182-431 of human EZH2 ( NP_004447) produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
EZH2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
EZH2
Gene Alias:
ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2146
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI10B10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q15910
Gene Symbols:
EZH2
Immunogen:
Human recombit protein fragment corresponding to amino acids 182-431 of human EZH2 ( NP_004447) produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
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