50-166-6610

IRAK2 Mouse anti-Human, Clone: OTI4C1, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-6610-Each-of-1 In Stock ₹ 58,009.68

50-166-6610 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

IRAK2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

IRAK2

Gene Alias

IRAK-2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3656

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4C1

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O43187

Gene Symbols

IRAK2

Immunogen

Human recombit protein fragment corresponding to amino acids 362-625 of human IRAK2 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO IRAK2 (interleukin-1 receptor-associated kinase-like 2) binds to the IL-1 type I receptor following IL-1 engagment and triggers intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization
  • The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP)
  • IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappa-B , which is a pivotal transcription factor mediating inflammatory and immune response
  • A novel member in the IRAK/Pelle family was recently identified and designated IRAK2
  • Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappa-B activation
  • IRAKs also associate with Toll-like receptor (TLR) and the domit negative mutants of IRAKs inhibit LPS-induced NF-kappa-B activation
  • Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory responses to cytokine IL-1 and LPS
  • IRAK2 is expressed in a variety of human tissues.

Compare Similar Items

Show Difference

Img

OriGene

50-166-6610

--


Antigen:
IRAK2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IRAK2

Gene Alias:
IRAK-2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3656

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4C1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O43187

Gene Symbols:
IRAK2

Immunogen:
Human recombit protein fragment corresponding to amino acids 362-625 of human IRAK2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6611

--


Antigen:
APC

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
APC

Gene Alias:
BTPS2, DP2, DP2.5, DP3, GS, PPP1R46

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
324

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2B8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P25054

Gene Symbols:
APC

Immunogen:
Human recombit protein fragment corresponding to amino acids 955-1382 of human APC produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6612

--


Antigen:
ABCD1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ABCD1

Gene Alias:
ABC42, ALD, ALDP, AMN

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
215

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5G6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P33897

Gene Symbols:
ABCD1

Immunogen:
Human recombit protein fragment corresponding to amino acids 508-745 of human ABCD1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-6613

--


Antigen:
ARAF

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ARAF

Gene Alias:
A-RAF, ARAF1, PKS2, RAFA1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
369

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2F8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P10398

Gene Symbols:
ARAF

Immunogen:
Human recombit protein fragment corresponding to amino acids 145-365 of human ARAF produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1