50-166-6769
TNFRSF8 Mouse anti-Human, Clone: OTI8D7, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-6769-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-6769 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
TNFRSF8
Classification
Monoclonal
Conjugate
Unconjugated
Gene
TNFRSF8
Gene Alias
CD30, D1S166E, Ki-1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
943
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Flow Cytometry
Clone
OTI8D7
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P28908
Gene Symbols
TNFRSF8
Immunogen
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO CD30 (Ki-1, TNF Receptor Superfamily Member 8) is a type I transmembrane glycoprotein of the TNF receptor superfamily
- CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1
- The ligand for CD30 is CD30L (CD153)
- The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
- CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas
- CD30 acts as a costimulatory molecule in thymic negative selection
- In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
- In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor
- Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response
- TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB
- CD30 is a positive regulator of apoptosis, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity
- Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
- CD30 is expressed by mononuclear cells in Hodgkin′s lymphoma, Reed Sternberg cells and most Anaplastic Large Cell Lymphomas (ALCL)
- CD30 is also expressed by embryonal carcinomas.
Compare Similar Items
Show Difference
Antigen: TNFRSF8
Classification: Monoclonal
Conjugate: Unconjugated
Gene: TNFRSF8
Gene Alias: CD30, D1S166E, Ki-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 943
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry
Clone: OTI8D7
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P28908
Gene Symbols: TNFRSF8
Immunogen: Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
TNFRSF8
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry
Clone:
OTI8D7
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: TNFRSF8
Classification: Monoclonal
Conjugate: Unconjugated
Gene: TNFRSF8
Gene Alias: CD30, D1S166E, Ki-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 943
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry
Clone: OTI13D8
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P28908
Gene Symbols: TNFRSF8
Immunogen: Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
TNFRSF8
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry
Clone:
OTI13D8
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: TNFRSF8
Classification: Monoclonal
Conjugate: Unconjugated
Gene: TNFRSF8
Gene Alias: CD30, D1S166E, Ki-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 943
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry
Clone: OTI1B2
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P28908
Gene Symbols: TNFRSF8
Immunogen: Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
TNFRSF8
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry
Clone:
OTI1B2
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: CD34
Classification: Monoclonal
Conjugate: Unconjugated
Gene: CD34
Gene Alias: CD34 molecule
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 947
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Flow Cytometry
Clone: OTI51A1
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P28906
Gene Symbols: CD34
Immunogen: HEK293T cells transfected with full length human CD34 gene (RC204446)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
CD34
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
CD34
Gene Alias:
CD34 molecule
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
947
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Flow Cytometry
Clone:
OTI51A1
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P28906
Gene Symbols:
CD34
Immunogen:
HEK293T cells transfected with full length human CD34 gene (RC204446)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a