50-166-7549

IGF1 Mouse anti-Human, Clone: OTI4B12, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-7549-Each-of-1 In Stock ₹ 58,009.68

50-166-7549 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

IGF1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

IGF1

Gene Alias

IGF-I, IGFI, MGF

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3479

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4B12

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P05019

Gene Symbols

IGF1

Immunogen

Human recombit protein fragment corresponding to amino acids 1-151 of human IGF1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
  • A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
  • Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
  • IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
  • In circulation, IGFs are predomitly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
  • IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
  • Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
  • Low levels of IGF1 have been linked to Alzheimer′s disease
  • IGF1 is processed from a precursor, bound by a specific receptor, and secreted
  • Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.

Compare Similar Items

Show Difference

Img

OriGene

50-166-7549

--


Antigen:
IGF1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IGF1

Gene Alias:
IGF-I, IGFI, MGF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4B12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-151 of human IGF1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-7550

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Antigen:
ESRRB

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ESRRB

Gene Alias:
DFNB35, ERR2, ERRb, ESRL2, NR3B2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2103

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI12H2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95718

Gene Symbols:
ESRRB

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-252 of human ESRRB produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-7551

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Antigen:
CDKL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CDKL2

Gene Alias:
KKIAMRE, P56

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8999

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI10H3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q92772

Gene Symbols:
CDKL2

Immunogen:
Human recombit protein fragment corresponding to amino acids 291-493 of human CDKL2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-7552

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Antigen:
RET

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RET

Gene Alias:
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5979

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1G1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P07949

Gene Symbols:
RET

Immunogen:
Human recombit protein fragment corresponding to amino acids 713-1017 of human RET produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1