50-166-7928

BCL2 Mouse anti-Human, Clone: OTI5H4, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-7928-Each-of-1 In Stock ₹ 58,009.68

50-166-7928 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

BCL2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

BCL2

Gene Alias

Bcl-2, PPP1R50

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

596

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI5H4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P10415

Gene Symbols

BCL2

Immunogen

Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

Show Difference

Img

OriGene

50-166-7928

--


Antigen:
BCL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BCL2

Gene Alias:
Bcl-2, PPP1R50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5H4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P10415

Gene Symbols:
BCL2

Immunogen:
Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-7929

--


Antigen:
BCL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BCL2

Gene Alias:
Bcl-2, PPP1R50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3B8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P10415

Gene Symbols:
BCL2

Immunogen:
Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-7931

--


Antigen:
BCL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BCL2

Gene Alias:
Bcl-2, PPP1R50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5F8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P10415

Gene Symbols:
BCL2

Immunogen:
Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-7933

--


Antigen:
BCL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BCL2

Gene Alias:
Bcl-2, PPP1R50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4C1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P10415

Gene Symbols:
BCL2

Immunogen:
Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1