50-166-7980

JAK2 Mouse anti-Human, Mouse, Clone: OTI1H9, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-7980-Each-of-1 In Stock ₹ 58,009.68

50-166-7980 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

JAK2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

JTK10, THCYT3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16452, 3717

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI1H9

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O60674, Q62120

Gene Symbols

JAK2

Immunogen

Human recombit protein fragment corresponding to amino acids 297-596 of human JAK2 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Janus Activating Kinase 2 (JAK2) is a non-rececptor tyrosine kinase involved in various processes such as cell growth, development, differentiation, and histone modifications
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting this gene can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

Show Difference

Img

OriGene

50-166-7980

--


Antigen:
JAK2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
JTK10, THCYT3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16452, 3717

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O60674, Q62120

Gene Symbols:
JAK2

Immunogen:
Human recombit protein fragment corresponding to amino acids 297-596 of human JAK2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-7982

--


Antigen:
CTGF

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CTGF

Gene Alias:
CCN2, HCS24, IGFBP8, NOV2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1490

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5C10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P29279

Gene Symbols:
CTGF

Immunogen:
Human recombit protein fragment corresponding to amino acids 27-349 of human CTGF produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-7986

--


Antigen:
FLT4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FLT4

Gene Alias:
FLT-4, FLT41, LMPH1A, PCL, VEGFR-3, VEGFR3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2324

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1G2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P35916

Gene Symbols:
FLT4

Immunogen:
Human recombit protein fragment corresponding to amino acids 1063-1363 of human FLT4 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-7987

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Antigen:
PDCD1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDCD1

Gene Alias:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4F10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q15116

Gene Symbols:
PDCD1

Immunogen:
Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1