50-166-7980

JAK2 Mouse anti-Human, Mouse, Clone: OTI1H9, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-7980-Each-of-1 In Stock ₹ 60,342.00

50-166-7980 - Each of 1

₹ 60,342.00

In Stock

Quantity

1

Base Price: ₹ 60,342.00

GST (18%): ₹ 10,861.56

Total Price: ₹ 71,203.56

Antigen

JAK2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

JTK10, THCYT3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16452, 3717

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI1H9

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O60674, Q62120

Gene Symbols

JAK2

Immunogen

Human recombit protein fragment corresponding to amino acids 297-596 of human JAK2 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Janus Activating Kinase 2 (JAK2) is a non-rececptor tyrosine kinase involved in various processes such as cell growth, development, differentiation, and histone modifications
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting this gene can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

Show Difference

Img

OriGene

50-166-7980

--


Antigen:
JAK2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
JTK10, THCYT3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16452, 3717

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O60674, Q62120

Gene Symbols:
JAK2

Immunogen:
Human recombit protein fragment corresponding to amino acids 297-596 of human JAK2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-7982

--


Antigen:
CTGF

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CTGF

Gene Alias:
CCN2, HCS24, IGFBP8, NOV2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1490

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5C10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P29279

Gene Symbols:
CTGF

Immunogen:
Human recombit protein fragment corresponding to amino acids 27-349 of human CTGF produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-7986

--


Antigen:
FLT4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FLT4

Gene Alias:
FLT-4, FLT41, LMPH1A, PCL, VEGFR-3, VEGFR3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2324

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1G2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P35916

Gene Symbols:
FLT4

Immunogen:
Human recombit protein fragment corresponding to amino acids 1063-1363 of human FLT4 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-7987

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Antigen:
PDCD1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDCD1

Gene Alias:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4F10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q15116

Gene Symbols:
PDCD1

Immunogen:
Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1