50-166-8034

ITGB1 Mouse anti-Human, Clone: OTI2A3, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8034-Each-of-1 In Stock ₹ 58,009.68

50-166-8034 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

ITGB1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ITGB1

Gene Alias

CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3688

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI2A3

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P05556

Gene Symbols

ITGB1

Immunogen

Full length human recombit protein of human ITGB1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD29 (beta1 integrin subunit, GPIIa) forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CD49a-f) determining the binding properties of beta1 (VLA) integrins
  • These integrins mediate cell adhesion to collagen, fibronectin, laminin and other extracellular matrix (ECM) components
  • This interaction hinders cell death, whereas disruption of anchorage to ECM leads to apoptosis
  • Decreased expression of most beta1 integrins correlates with acquiring multidrug resistance of tumor cells during selection in presence of antitumor drug
  • In platelets, translocation of intracellular pool of beta1 integrins to the plasma membrane following thrombin stimulation
  • These integrins are also up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue, as well as in regulating tissue damage and disease symptoms related to inflammatory bowel disease
  • Through a beta1 integrin-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8034

--


Antigen:
ITGB1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ITGB1

Gene Alias:
CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3688

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2A3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P05556

Gene Symbols:
ITGB1

Immunogen:
Full length human recombit protein of human ITGB1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8036

--


Antigen:
MMP3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MMP3

Gene Alias:
CHDS6, MMP-3, SL-1, STMY, STMY1, STR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4314

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3C6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P08254

Gene Symbols:
MMP3

Immunogen:
Human recombit protein fragment corresponding to amino acids 246-477 of human MMP3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8037

--


Antigen:
MMP3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MMP3

Gene Alias:
CHDS6, MMP-3, SL-1, STMY, STMY1, STR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4314

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2E7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P08254

Gene Symbols:
MMP3

Immunogen:
Human recombit protein fragment corresponding to amino acids 246-477 of human MMP3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-8038

--


Antigen:
DVL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
DVL2

Gene Alias:
dishevelled segment polarity protein 2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1856

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2E11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O14641

Gene Symbols:
DVL2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-320 of human DVL2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1