50-166-8045

PDCD1 Mouse anti-Human, Clone: OTI14C5, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8045-Each-of-1 In Stock ₹ 58,009.68

50-166-8045 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

PDCD1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PDCD1

Gene Alias

CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5133

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone

OTI14C5

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q15116

Gene Symbols

PDCD1

Immunogen

Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO PD-1 (Programmed Cell Death Protein 1, PCDP-1, CD279) is a cell surface receptor approximately 273-290 amino acids in length that inhibits cell-mediated immune responses initiated by T lymphocytes
  • PD-1 can bind two different but related ligands, PDL-1 and PDL-2
  • Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as lipopolysaccharide (LPS) associated with bacteria or pathogens
  • Evidence for this is seen in PD1-null mice who exhibit hyper-activated immune systems and autoimmune diseases
  • Further, expression of this gene in mice is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis
  • Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8045

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Antigen:
PDCD1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDCD1

Gene Alias:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI14C5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q15116

Gene Symbols:
PDCD1

Immunogen:
Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-8046

--


Antigen:
RORB

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RORB

Gene Alias:
NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6096

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4B7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q92753

Gene Symbols:
RORB

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-260 of human RORB produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8047

--


Antigen:
RORB

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RORB

Gene Alias:
NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6096

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1C11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q92753

Gene Symbols:
RORB

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-260 of human RORB produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-8048

--


Antigen:
TP53BP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TP53BP1

Gene Alias:
53BP1, TDRD30, TP53, p202, p53BP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7158

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6D9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q12888

Gene Symbols:
TP53BP1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-300 of human TP53BP1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b