50-166-8156

CD3 Mouse anti-Human, Clone: UCHT1, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8156-Each-of-1 In Stock ₹ 58,009.68

50-166-8156 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CD3

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CD3E

Gene Alias

IMD18; T3E; TCRE; HCD3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

916

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Western Blot

Clone

UCHT1

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P07766

Gene Symbols

CD3E

Immunogen

Human infant thymocytes and lymphocytes from a patient with Sezary disease

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD3 epsilon is part of the CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex
  • T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta
  • These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11
  • The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits
  • CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation
  • The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum
  • It is never expressed on B or NK cells
  • Decreased percentages of T lymphocytes may be observed in some autoimmune diseases
  • The genes encoding the CD3 epsilon, gamma and delta polypeptides are located on chromosome 11
  • Defects in this gene are associated with T cell immunodeficiency and has been linked to Type 1 Diabetes deficiency in women.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8156

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Antigen:
CD3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD3E

Gene Alias:
IMD18; T3E; TCRE; HCD3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
916

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Clone:
UCHT1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P07766

Gene Symbols:
CD3E

Immunogen:
Human infant thymocytes and lymphocytes from a patient with Sezary disease

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8158

--


Antigen:
UBA52

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
UBA52

Gene Alias:
CEP52, HUBCEP52, L40, RPL40

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7311

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4F2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P62987

Gene Symbols:
UBA52

Immunogen:
Synthetic peptide corresponding to residues near C-terminus of human UBA52.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8159

--


Antigen:
PDCD1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDCD1

Gene Alias:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI17G9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q15116

Gene Symbols:
PDCD1

Immunogen:
Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8160

--


Antigen:
TP53BP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TP53BP1

Gene Alias:
53BP1, TDRD30, TP53, p202, p53BP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7158

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI9C8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q12888

Gene Symbols:
TP53BP1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-300 of human TP53BP1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1