50-166-8216

TNFRSF10B Mouse anti-Human, Mouse, Clone: OTI2A5, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8216-Each-of-1 In Stock ₹ 58,009.68

50-166-8216 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

TNFRSF10B

Classification

Monoclonal

Conjugate

Unconjugated

Gene

TNFRSF10B

Gene Alias

CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21933, 8795

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2A5

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O14763, Q9QZM4

Gene Symbols

Tnfrsf10b

Immunogen

Human recombit protein fragment corresponding to amino acids 203-411 of human TNFRSF10B produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO DR5 (Apo2, TRAIL-R2, TRICK2, KILLER) is a recently identified death domain containing receptor for TRAIL, which mediates TRAIL induced apoptosis
  • DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain
  • DR5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal
  • Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by DR5
  • Two transcript variants encoding different isoforms of DR5 and one non-coding transcript have been found
  • Overexpression of DR5 induces apoptosis and activates NF-kappa-B
  • DR5 is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen
  • Diseases associated with DR5 dysfunction include squamous cell carcinoma, and diffuse infiltrative lymphocytosis syndrome.

Compare Similar Items

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Img

OriGene

50-166-8216

--


Antigen:
TNFRSF10B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFRSF10B

Gene Alias:
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21933, 8795

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2A5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O14763, Q9QZM4

Gene Symbols:
Tnfrsf10b

Immunogen:
Human recombit protein fragment corresponding to amino acids 203-411 of human TNFRSF10B produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8217

--


Antigen:
MALT1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MALT1

Gene Alias:
IMD12, MLT, MLT1, PCASP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10892

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4C3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UDY8

Gene Symbols:
MALT1

Immunogen:
Full length human recombit protein of human MALT1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8218

--


Antigen:
MALT1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MALT1

Gene Alias:
IMD12, MLT, MLT1, PCASP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10892

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4H10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UDY8

Gene Symbols:
MALT1

Immunogen:
Full length human recombit protein of human MALT1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-8219

--


Antigen:
MALT1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MALT1

Gene Alias:
IMD12, MLT, MLT1, PCASP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10892

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI3E10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UDY8

Gene Symbols:
MALT1

Immunogen:
Full length human recombit protein of human MALT1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1