50-166-8341

CD40 Mouse anti-Human, Clone: OTI8B8, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8341-Each-of-1 In Stock ₹ 58,009.68

50-166-8341 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CD40

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CD40

Gene Alias

Bp50, CDW40, TNFRSF5, p50

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

958

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI8B8

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P25942

Gene Symbols

CD40

Immunogen

Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin′s disease associated antigen, CD30
  • CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells
  • CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation
  • AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which may be important for homotypic cell interactions
  • Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction
  • The interaction of CD40 and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis
  • Two alternatively spliced transcript variants of CD40 encoding distinct isoforms have been reported
  • Diseases associated with CD40 dysfunction include Type 3 Hyper-Igm immunodeficiency and CD40 ligand deficiency.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8341

--


Antigen:
CD40

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
Bp50, CDW40, TNFRSF5, p50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8B8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P25942

Gene Symbols:
CD40

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-8343

--


Antigen:
CD40

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
Bp50, CDW40, TNFRSF5, p50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8G5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P25942

Gene Symbols:
CD40

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8344

--


Antigen:
CD40

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
Bp50, CDW40, TNFRSF5, p50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI8C5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P25942

Gene Symbols:
CD40

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-8345

--


Antigen:
CD40

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
Bp50, CDW40, TNFRSF5, p50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6C12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P25942

Gene Symbols:
CD40

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1