50-166-8362

CDCA8 Mouse anti-Human, Clone: OTI7G7, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-8362-Each-of-1 In Stock ₹ 58,009.68

50-166-8362 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CDCA8

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CDCA8

Gene Alias

BOR, BOREALIN, DasraB, MESRGP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55143

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI7G7

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q53HL2

Gene Symbols

CDCA8

Immunogen

Full length human recombit protein of human CDCA8 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle
  • The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division
  • It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase
  • CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues
  • In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation
  • Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53
  • Its aberrant expression is linked to a poor prognosis for gastric cancer.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8362

--


Antigen:
CDCA8

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CDCA8

Gene Alias:
BOR, BOREALIN, DasraB, MESRGP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55143

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI7G7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q53HL2

Gene Symbols:
CDCA8

Immunogen:
Full length human recombit protein of human CDCA8 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-8363

--


Antigen:
POLA2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
POLA2

Gene Alias:
DNA polymerase alpha 2, accessory subunit

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23649

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3F2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q14181

Gene Symbols:
POLA2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-284 of human POLA2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8365

--


Antigen:
PELI1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PELI1

Gene Alias:
pellino E3 ubiquitin protein ligase 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1A8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q96FA3

Gene Symbols:
PELI1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-245 of human PELI1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8366

--


Antigen:
PELI1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PELI1

Gene Alias:
pellino E3 ubiquitin protein ligase 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3A9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q96FA3

Gene Symbols:
PELI1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-245 of human PELI1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1