50-166-8389

PDGFRA Mouse anti-Human, Clone: OTI1C10, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8389-Each-of-1 In Stock ₹ 58,009.68

50-166-8389 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

PDGFRA

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PDGFRA

Gene Alias

CD140A, PDGFR-2, PDGFR2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5156

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1C10

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P16234

Gene Symbols

PDGFRA

Immunogen

Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO PDGFRA (PDGFR-alpha, Platelet Derived Growth Factor Receptor alpha) belongs to the protein tyrosine kinase family, and binds to the alpha chain of PDGF
  • PDGFR exhibits two different isoforms, alpha and beta, which are coded by two different genes
  • PDGF-alpha receptors are expressed in oligodendrocyte progenitor cells while PDGF-beta receptors are expressed on neurons
  • PDGFR possess five immunoglobulin like domains that are involved in ligand binding
  • Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind
  • PDGF AA can bind and activate only PDGFR alpha, while PDGF BB can bind and activate both PDGFR alpha and beta
  • Members of the PDGF receptor subfamily are cell surface receptors that act as mitogens for cells of mesenchymal origin, and consist of alpha and beta isoforms of ∽190 and 125 kDa, respectively
  • Activated PDGF receptors act on signaling pathways that control cell growth, actin reorganization, migration, and differentiation
  • In humans, the gene is located on the q arm of chromosome 4
  • Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8389

--


Antigen:
PDGFRA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDGFRA

Gene Alias:
CD140A, PDGFR-2, PDGFR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5156

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P16234

Gene Symbols:
PDGFRA

Immunogen:
Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8390

--


Antigen:
CSF3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CSF3

Gene Alias:
C17orf33, CSF3OS, GCSF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1440

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI7B3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P09919

Gene Symbols:
CSF3

Immunogen:
Human recombit protein fragment corresponding to amino acids 30-200 of human CSF3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8391

--


Antigen:
TNFRSF10A

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFRSF10A

Gene Alias:
APO2, CD261, DR4, TRAILR-1, TRAILR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8797

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI11B12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O00220

Gene Symbols:
TNFRSF10A

Immunogen:
Human recombit protein fragment corresponding to amino acids 263-468 of human TNFRSF10A produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8392

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Antigen:
MEF2D

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MEF2D

Gene Alias:
myocyte enhancer factor 2D

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4209

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q14814

Gene Symbols:
MEF2D

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-282 of human MEF2D produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1