50-166-8475

IL15 Mouse anti-Human, Clone: OTI2B4, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8475-Each-of-1 In Stock ₹ 58,009.68

50-166-8475 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

IL15

Classification

Monoclonal

Conjugate

Unconjugated

Gene

IL15

Gene Alias

IL-15

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3600

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI2B4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P40933

Gene Symbols

IL15

Immunogen

Human recombit protein fragment corresponding to amino acids 49-162 of human IL15 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Related Products

Img

OriGene

50-166-8642

--

Img

OriGene

50-166-8258

--

Img

OriGene

50-166-2387

--

Img

OriGene

50-166-2380

--

Img

OriGene

50-166-8507

--

Img

OriGene

50-166-8684

--

Img

OriGene

50-166-8297

--

Img

OriGene

50-166-8298

--

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation
  • IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other′s activity
  • The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2
  • IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6
  • In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis
  • IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules
  • As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases
  • Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases
  • Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8475

--


Antigen:
IL15

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IL15

Gene Alias:
IL-15

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3600

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2B4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P40933

Gene Symbols:
IL15

Immunogen:
Human recombit protein fragment corresponding to amino acids 49-162 of human IL15 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8479

--


Antigen:
SCML2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SCML2

Gene Alias:
Scm polycomb group protein like 2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10389

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UQR0

Gene Symbols:
SCML2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-321 of human SCML2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8480

--


Antigen:
FIGF

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VEGFD

Gene Alias:
FIGF, VEGF-D

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2277

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2A1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O43915

Gene Symbols:
VEGFD

Immunogen:
Human recombit protein fragment corresponding to amino acids 89-205 of human FIGF produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8484

--


Antigen:
SCML2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SCML2

Gene Alias:
Scm polycomb group protein like 2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10389

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1B1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UQR0

Gene Symbols:
SCML2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-321 of human SCML2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b