50-166-8505

TNFA Mouse anti-Human, Clone: OTI5A11, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8505-Each-of-1 In Stock ₹ 58,009.68

50-166-8505 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

TNFA

Classification

Monoclonal

Conjugate

Unconjugated

Gene

TNF

Gene Alias

DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7124

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Clone

OTI5A11

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P01375

Gene Symbols

TNF

Immunogen

Full length human recombit protein of human TNFA produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
  • This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
  • TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
  • TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
  • Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
  • Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
  • TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
  • This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8505

--


Antigen:
TNFA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNF

Gene Alias:
DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7124

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI5A11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P01375

Gene Symbols:
TNF

Immunogen:
Full length human recombit protein of human TNFA produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8507

--


Antigen:
IGFBP3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IGFBP3

Gene Alias:
BP-53, IBP3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3486

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI16B1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P17936

Gene Symbols:
IGFBP3

Immunogen:
Human recombit protein fragment corresponding to amino acids 28-297 of human IGFBP3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8508

--


Antigen:
CD22

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD22

Gene Alias:
SIGLEC-2, SIGLEC2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
933

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2B12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P20273

Gene Symbols:
CD22

Immunogen:
Human recombit protein fragment corresponding to amino acids 707-847 of human CD22 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8509

--


Antigen:
CD22

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD22

Gene Alias:
SIGLEC-2, SIGLEC2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
933

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2E6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P20273

Gene Symbols:
CD22

Immunogen:
Human recombit protein fragment corresponding to amino acids 707-847 of human CD22 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b