50-166-8515

IGF1R Mouse anti-Human, Clone: OTI11E4, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-8515-Each-of-1 In Stock ₹ 58,009.68

50-166-8515 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

IGF1R

Classification

Monoclonal

Conjugate

Unconjugated

Gene

IGF1R

Gene Alias

CD221, IGFIR, IGFR, JTK13

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3480

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI11E4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P08069

Gene Symbols

IGF1R

Immunogen

Human recombit protein fragment corresponding to amino acids 741-935 of human IGF1R produced in Insect.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Insulin growth factor 1 receptor belongs to the family of tyrosine receptor kinases
  • It is involved in activation of various substrates including IGF and neurotensin, regulation of metabolism, cell division, maintece, and inflammation response
  • The protein is a tetramer consisting of two alpha, and two beta subunits
  • The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2
  • Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136
  • The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8515

--


Antigen:
IGF1R

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
CD221, IGFIR, IGFR, JTK13

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3480

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI11E4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P08069

Gene Symbols:
IGF1R

Immunogen:
Human recombit protein fragment corresponding to amino acids 741-935 of human IGF1R produced in Insect.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8517

--


Antigen:
NAPSA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NAPSA

Gene Alias:
KAP, Kdap, NAP1, NAPA, SNAPA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9476

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence

Clone:
OTI4G9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Human recombit protein fragment corresponding to amino acids 64-244 of human NAPSA produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-8522

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Antigen:
EGFL7

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
EGFL7

Gene Alias:
NEU1, VE-STATIN, ZNEU1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4A5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UHF1

Gene Symbols:
EGFL7

Immunogen:
Human recombit protein fragment corresponding to amino acids 24-273 of human EGFL7 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8528

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Antigen:
ZFP42

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ZFP42

Gene Alias:
REX-1, REX1, ZNF754, zfp-42

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
132625

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI9E8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q96MM3

Gene Symbols:
ZFP42

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-235 of human ZFP42 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1