50-166-8562
Beta-catenin Mouse anti-Human, Clone: OTI2F10, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-8562-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-8562 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
Beta-catenin
Classification
Monoclonal
Conjugate
Unconjugated
Gene
CTNNB1
Gene Alias
CTNNB, EVR7, MRD19, armadillo
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1499
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2F10
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P35222
Gene Symbols
CTNNB1
Immunogen
Human recombit protein fragment corresponding to amino acids 29-118 of human CTNNB1 produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
- AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
- Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
- Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
- The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
- Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
- A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
- In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
- The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.
Compare Similar Items
Show Difference
Antigen: Beta-catenin
Classification: Monoclonal
Conjugate: Unconjugated
Gene: CTNNB1
Gene Alias: CTNNB, EVR7, MRD19, armadillo
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1499
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2F10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P35222
Gene Symbols: CTNNB1
Immunogen: Human recombit protein fragment corresponding to amino acids 29-118 of human CTNNB1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Beta-catenin
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
CTNNB1
Gene Alias:
CTNNB, EVR7, MRD19, armadillo
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1499
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2F10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P35222
Gene Symbols:
CTNNB1
Immunogen:
Human recombit protein fragment corresponding to amino acids 29-118 of human CTNNB1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: TGFBR2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: TGFBR2
Gene Alias: AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7048
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI3B4
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P37173
Gene Symbols: TGFBR2
Immunogen: Human recombit protein fragment corresponding to amino acids 23-294 of human TGFBR2 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
TGFBR2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TGFBR2
Gene Alias:
AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7048
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI3B4
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P37173
Gene Symbols:
TGFBR2
Immunogen:
Human recombit protein fragment corresponding to amino acids 23-294 of human TGFBR2 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: POU2AF1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: POU2AF1
Gene Alias: BOB1, OBF-1, OBF1, OCAB
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5450
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI2D4
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q16633
Gene Symbols: POU2AF1
Immunogen: Full length human recombit protein of human POU2AF1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
POU2AF1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
POU2AF1
Gene Alias:
BOB1, OBF-1, OBF1, OCAB
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5450
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI2D4
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q16633
Gene Symbols:
POU2AF1
Immunogen:
Full length human recombit protein of human POU2AF1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: MED15
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MED15
Gene Alias: ARC105, CAG7A, CTG7A, PCQAP, TIG-1, TIG1, TNRC7
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51586
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1H5
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q96RN5
Gene Symbols: MED15
Immunogen: Human recombit protein fragment corresponding to amino acids 393-679 of human MED15 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
MED15
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MED15
Gene Alias:
ARC105, CAG7A, CTG7A, PCQAP, TIG-1, TIG1, TNRC7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51586
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1H5
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q96RN5
Gene Symbols:
MED15
Immunogen:
Human recombit protein fragment corresponding to amino acids 393-679 of human MED15 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1