50-166-8672

ALAS1 Mouse anti-Human, Clone: OTI1C5, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-8672-Each-of-1 In Stock ₹ 58,009.68

50-166-8672 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

ALAS1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ALAS1

Gene Alias

ALAS, ALAS-H, ALAS3, ALASH, MIG4

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

211

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI1C5

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P13196

Gene Symbols

ALAS1

Immunogen

Human recombit protein fragment corresponding to amino acids 57-308 of human ALAS1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO ALAS-1 is a nuclear-encoded mitochondrial matrix enzyme which catalyzes the condensation of glycine with succinyl-CoA to form delta-amino levulinate, CO2 and CoA
  • It regulates the first and rate-limiting step of heme biosynthetic pathway
  • It is one of the two isoforms of ALAS and is a pyridoxal-5′ phosphate dependant housekeeping enzyme
  • It is ubiquitously expressed and is responsible of providing heme for cytochromes and other hemoproteins
  • ALAS1 in liver undergoes negative feedback regulation by heme
  • Transcription of ALAS1 gene is stimulated by cAMP and respiratory uncoupling whereas Phorbol esters and insulin repress ALAS1 gene expression
  • ALAS1 is suggested to be involved in reciprocal regulation of Heme biosynthesis and circadian clock suggesting a potential target for treatment of circadian disorders
  • ALAS1 gene expression is down regulated in Acute Liver failure resulting in altered heme metabolism and liver function.

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OriGene

50-166-8672

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Antigen:
ALAS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ALAS1

Gene Alias:
ALAS, ALAS-H, ALAS3, ALASH, MIG4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1C5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P13196

Gene Symbols:
ALAS1

Immunogen:
Human recombit protein fragment corresponding to amino acids 57-308 of human ALAS1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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OriGene

50-166-8673

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Antigen:
POTEG

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
POTEG

Gene Alias:
A26C2, ACTBL1, CT104.4, POTE-14, POTE14, POTE14alpha, POTE22

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
404785

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI10A7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q6S5H5

Gene Symbols:
POTEG

Immunogen:
Full length human recombit protein of human POTEG produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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OriGene

50-166-8674

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Antigen:
CDC42SE2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CDC42SE2

Gene Alias:
SPEC2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56990

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1B2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9NRR3

Gene Symbols:
CDC42SE2

Immunogen:
Full length human recombit protein of human CDC42SE2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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Antigen:
MED6

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MED6

Gene Alias:
ARC33, NY-REN-28

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10001

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3C9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O75586

Gene Symbols:
MED6

Immunogen:
Full length human recombit protein of human MED6 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1