50-166-8683

ALAS1 Mouse anti-Human, Clone: OTI5D5, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-8683-Each-of-1 In Stock ₹ 58,009.68

50-166-8683 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

ALAS1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ALAS1

Gene Alias

ALAS, ALAS-H, ALAS3, ALASH, MIG4

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

211

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI5D5

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P13196

Gene Symbols

ALAS1

Immunogen

Human recombit protein fragment corresponding to amino acids 57-308 of human ALAS1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO ALAS-1 is a nuclear-encoded mitochondrial matrix enzyme which catalyzes the condensation of glycine with succinyl-CoA to form delta-amino levulinate, CO2 and CoA
  • It regulates the first and rate-limiting step of heme biosynthetic pathway
  • It is one of the two isoforms of ALAS and is a pyridoxal-5′ phosphate dependant housekeeping enzyme
  • It is ubiquitously expressed and is responsible of providing heme for cytochromes and other hemoproteins
  • ALAS1 in liver undergoes negative feedback regulation by heme
  • Transcription of ALAS1 gene is stimulated by cAMP and respiratory uncoupling whereas Phorbol esters and insulin repress ALAS1 gene expression
  • ALAS1 is suggested to be involved in reciprocal regulation of Heme biosynthesis and circadian clock suggesting a potential target for treatment of circadian disorders
  • ALAS1 gene expression is down regulated in Acute Liver failure resulting in altered heme metabolism and liver function.

Compare Similar Items

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Img

OriGene

50-166-8683

--


Antigen:
ALAS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ALAS1

Gene Alias:
ALAS, ALAS-H, ALAS3, ALASH, MIG4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5D5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P13196

Gene Symbols:
ALAS1

Immunogen:
Human recombit protein fragment corresponding to amino acids 57-308 of human ALAS1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8684

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Antigen:
IL12RB1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IL12RB1

Gene Alias:
CD212, IL-12R-BETA1, IL12RB, IMD30

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3594

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1A6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P42701

Gene Symbols:
IL12RB1

Immunogen:
Human recombit protein fragment corresponding to amino acids 33-283 of human IL12RB1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8685

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Antigen:
BTG2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BTG2

Gene Alias:
APRO1, PC3, TIS21

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7832

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4C10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P78543

Gene Symbols:
BTG2

Immunogen:
Full length human recombit protein of human BTG2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8686

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Antigen:
EIF3D

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
EIF3D

Gene Alias:
EIF3S7, eIF3-p66, eIF3-zeta

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8664

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI14D6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O15371

Gene Symbols:
EIF3D

Immunogen:
Full length human recombit protein of human EIF3D produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1