50-166-8806

MST1 Mouse anti-Human, Clone: OTI4B12, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8806-Each-of-1 In Stock ₹ 58,009.68

50-166-8806 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

MST1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

MST1

Gene Alias

D3F15S2, DNF15S2, HGFL, MSP, NF15S2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4485

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI4B12

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P26927

Gene Symbols

MST1

Immunogen

Human recombit protein fragment corresponding to amino acids 194-462 of human MST1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO MST1 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
  • Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
  • STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8806

--


Antigen:
MST1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MST1

Gene Alias:
D3F15S2, DNF15S2, HGFL, MSP, NF15S2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4485

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4B12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P26927

Gene Symbols:
MST1

Immunogen:
Human recombit protein fragment corresponding to amino acids 194-462 of human MST1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8807

--


Antigen:
ABCC5

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ABCC5

Gene Alias:
ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10057

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6C6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O15440

Gene Symbols:
ABCC5

Immunogen:
Full length human recombit protein of human ABCC5 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8808

--


Antigen:
NKX2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NKX2-1

Gene Alias:
BCH, BHC, NK-2, NKX2.1, NKX2A, NMTC1, T/EBP, TEBP, TITF1, TTF-1, TTF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7080

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4F1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P43699

Gene Symbols:
NKX2-1

Immunogen:
Full length human recombit protein of human NKX2-1 ( NP_003308) produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8809

--


Antigen:
NKX2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NKX2-1

Gene Alias:
BCH, BHC, NK-2, NKX2.1, NKX2A, NMTC1, T/EBP, TEBP, TITF1, TTF-1, TTF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7080

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence

Clone:
OTI3D7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P43699

Gene Symbols:
NKX2-1

Immunogen:
Full length human recombit protein of human NKX2-1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1