50-166-8892

MST1 Mouse anti-Human, Clone: OTI1A10, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8892-Each-of-1 In Stock ₹ 58,009.68

50-166-8892 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

MST1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

MST1

Gene Alias

D3F15S2, DNF15S2, HGFL, MSP, NF15S2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4485

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1A10

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P26927

Gene Symbols

MST1

Immunogen

Human recombit protein fragment corresponding to amino acids 194-462 of human MST1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO MST1 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
  • Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
  • STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.

Compare Similar Items

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Img

OriGene

50-166-8892

--


Antigen:
MST1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MST1

Gene Alias:
D3F15S2, DNF15S2, HGFL, MSP, NF15S2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4485

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1A10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P26927

Gene Symbols:
MST1

Immunogen:
Human recombit protein fragment corresponding to amino acids 194-462 of human MST1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8894

--


Antigen:
MLPH

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MLPH

Gene Alias:
SLAC2-A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79083

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6E8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9BV36

Gene Symbols:
MLPH

Immunogen:
Human recombit protein fragment corresponding to amino acids 295-600 of human MLPH produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-8895

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Antigen:
CDKN1A

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CDKN1A

Gene Alias:
CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1026

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2D3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P38936

Gene Symbols:
CDKN1A

Immunogen:
Human recombit protein fragment corresponding to amino acids 2-164 of human CDKN1A produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8896

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Antigen:
MARK4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MARK4

Gene Alias:
MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57787

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI9B7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q96L34

Gene Symbols:
MARK4

Immunogen:
Human recombit protein fragment corresponding to amino acids 390-467 of human MARK4 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1