50-166-8936

IRS1 Mouse anti-Human, Clone: OTI3G10, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8936-Each-of-1 In Stock ₹ 58,009.68

50-166-8936 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

IRS1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

IRS1

Gene Alias

HIRS-1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3667

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3G10

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P35568

Gene Symbols

IRS1

Immunogen

Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
  • IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
  • An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
  • Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
  • Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
  • IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.

Compare Similar Items

Show Difference

Img

OriGene

50-166-8936

--


Antigen:
IRS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
HIRS-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3667

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3G10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P35568

Gene Symbols:
IRS1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8937

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Antigen:
LELP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LELP1

Gene Alias:
late cornified envelope like proline rich 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
149018

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2B4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q5T871

Gene Symbols:
LELP1

Immunogen:
Full length human recombit protein of human LELP1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8938

--


Antigen:
LELP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LELP1

Gene Alias:
late cornified envelope like proline rich 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
149018

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5B3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q5T871

Gene Symbols:
LELP1

Immunogen:
Full length human recombit protein of human LELP1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-8939

--


Antigen:
LELP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LELP1

Gene Alias:
late cornified envelope like proline rich 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
149018

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3C1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q5T871

Gene Symbols:
LELP1

Immunogen:
Full length human recombit protein of human LELP1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1