50-166-9391

ERBB3 Mouse anti-Human, Clone: OTI10D10, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-9391-Each-of-1 In Stock ₹ 58,009.68

50-166-9391 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

ERBB3

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2065

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI10D10

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P21860

Gene Symbols

ERBB3

Immunogen

Human recombit protein fragment corresponding to amino acids 983-1342 of human ERBB3 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Related Products

Img

OriGene

50-166-9252

--

Img

OriGene

50-166-9236

--

Img

OriGene

50-166-9229

--

Img

OriGene

50-166-8934

--

Img

OriGene

50-166-9275

--

Img

OriGene

50-166-9512

--

Img

OriGene

50-166-9272

--

Img

OriGene

50-166-9453

--

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6.2kb mRNA which is translated into a 160/180kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

Compare Similar Items

Show Difference

Img

OriGene

50-166-9391

--


Antigen:
ERBB3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI10D10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
Human recombit protein fragment corresponding to amino acids 983-1342 of human ERBB3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9392

--


Antigen:
GRB7

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GRB7

Gene Alias:
growth factor receptor bound protein 7

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2886

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6H2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q14451

Gene Symbols:
GRB7

Immunogen:
Full length human recombit protein of human GRB7 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-166-9393

--


Antigen:
GRB7

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GRB7

Gene Alias:
growth factor receptor bound protein 7

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2886

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI15E7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q14451

Gene Symbols:
GRB7

Immunogen:
Full length human recombit protein of human GRB7 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9394

--


Antigen:
PAMR1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PAMR1

Gene Alias:
DKFZP586H2123, FP938, RAMP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25891

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4E2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q6UXH9

Gene Symbols:
PAMR1

Immunogen:
Human recombit protein fragment corresponding to amino acids 338-559 of human PAMR1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b