50-166-9628
MAP3K7 Mouse anti-Human, Clone: OTI9D2, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-9628-Each-of-1 | In Stock | ₹ 60,342.00 |
50-166-9628 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,342.00
GST (18%): ₹ 10,861.56
Total Price: ₹ 71,203.56
Antigen
MAP3K7
Classification
Monoclonal
Conjugate
Unconjugated
Gene
MAP3K7
Gene Alias
CSCF, FMD2, MEKK7, TAK1, TGF1a
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6885
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Western Blot
Clone
OTI9D2
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
O43318
Gene Symbols
MAP3K7
Immunogen
Human recombit protein fragment corresponding to amino acids 254-367 of human MAP3K7 produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
- Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
- It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
- Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
- TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
- Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
- In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
- Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.
Compare Similar Items
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Antigen: MAP3K7
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MAP3K7
Gene Alias: CSCF, FMD2, MEKK7, TAK1, TGF1a
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6885
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI9D2
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: O43318
Gene Symbols: MAP3K7
Immunogen: Human recombit protein fragment corresponding to amino acids 254-367 of human MAP3K7 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
MAP3K7
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MAP3K7
Gene Alias:
CSCF, FMD2, MEKK7, TAK1, TGF1a
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6885
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI9D2
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
O43318
Gene Symbols:
MAP3K7
Immunogen:
Human recombit protein fragment corresponding to amino acids 254-367 of human MAP3K7 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: CLTA
Classification: Monoclonal
Conjugate: Unconjugated
Gene: CLTA
Gene Alias: LCA
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1211
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2C2
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P09496
Gene Symbols: CLTA
Immunogen: Full length human recombit protein of human CLTA produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG3
Antigen:
CLTA
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
CLTA
Gene Alias:
LCA
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1211
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2C2
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P09496
Gene Symbols:
CLTA
Immunogen:
Full length human recombit protein of human CLTA produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG3
Antigen: FAM170A
Classification: Monoclonal
Conjugate: Unconjugated
Gene: FAM170A
Gene Alias: ZNFD
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 340069
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI3A12
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: A1A519
Gene Symbols: FAM170A
Immunogen: Full length human recombit protein of human FAM170A produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
FAM170A
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
FAM170A
Gene Alias:
ZNFD
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
340069
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI3A12
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
A1A519
Gene Symbols:
FAM170A
Immunogen:
Full length human recombit protein of human FAM170A produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: CRP
Classification: Monoclonal
Conjugate: Unconjugated
Gene: CRP
Gene Alias: PTX1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1401
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1G10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P02741
Gene Symbols: CRP
Immunogen: Full length human recombit protein of human CRP produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CRP
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
CRP
Gene Alias:
PTX1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1401
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1G10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P02741
Gene Symbols:
CRP
Immunogen:
Full length human recombit protein of human CRP produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1