50-166-9818

CRY1 Mouse anti-Human, Clone: OTI6C6, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-9818-Each-of-1 In Stock ₹ 58,009.68

50-166-9818 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CRY1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CRY1

Gene Alias

DSPD, PHLL1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1407

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI6C6

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q16526

Gene Symbols

CRY1

Immunogen

Human recombit protein fragment corresponding to amino acids 502-584 of human CRY1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Various biochemical, physiological and behavioural processes display circadian rhythms controlled by an internal biological clock
  • The central ""gears"" driving this clock appear to be composed of an autoregulatory transcription/posttranslation-based feedback loop
  • Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases
  • In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function
  • Mammalian CRY1 and CRY2 function via light-independent interactions with circadian genes CLOCK and BMAL1, as well as with PER1, PER2, and TIM
  • They seem to act as light-independent components of the circadian clock and likely regulate Per1 transcriptional cycling via interactions with both the activator and its feedback inhibitors
  • Mutant mice not expressing the Cry1 or Cry2 protein display accelerated and delayed periodicity of locomotor activity, respectively
  • It appears that the combination of both proteins working together is essential to synchronize the organism to circadian phases
  • A critical balance between Cry1 and Cry2 is required for proper clock function; in complete darkness, double-mutant mice present with instantaneous arrhythmicity, indicating the absence of an internal circadian clock.

Compare Similar Items

Show Difference

Img

OriGene

50-166-9818

--


Antigen:
CRY1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CRY1

Gene Alias:
DSPD, PHLL1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1407

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6C6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q16526

Gene Symbols:
CRY1

Immunogen:
Human recombit protein fragment corresponding to amino acids 502-584 of human CRY1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9819

--


Antigen:
TEKT2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TEKT2

Gene Alias:
TEKTB1, TEKTIN-T, h-tektin-t

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27285

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1E6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UIF3

Gene Symbols:
TEKT2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-244 of human TEKT2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9820

--


Antigen:
TEKT2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TEKT2

Gene Alias:
TEKTB1, TEKTIN-T, h-tektin-t

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27285

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1E11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UIF3

Gene Symbols:
TEKT2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-244 of human TEKT2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9822

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Antigen:
ELF3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ELF3

Gene Alias:
EPR-1, ERT, ESE-1, ESX

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1999

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3F2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P78545

Gene Symbols:
ELF3

Immunogen:
Human recombit protein fragment corresponding to amino acids 175-286 of human ELF3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b