50-167-0249

TNFRSF8 Mouse anti-Human, Clone: OTI2H2, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-0249-Each-of-1 In Stock ₹ 58,009.68

50-167-0249 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

TNFRSF8

Classification

Monoclonal

Conjugate

Unconjugated

Gene

TNFRSF8

Gene Alias

CD30, D1S166E, Ki-1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

943

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI2H2

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P28908

Gene Symbols

TNFRSF8

Immunogen

Human recombit protein fragment corresponding to amino acids 408-595 of human TNFRSF8 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD30 (Ki-1, TNF Receptor Superfamily Member 8) is a type I transmembrane glycoprotein of the TNF receptor superfamily
  • CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1
  • The ligand for CD30 is CD30L (CD153)
  • The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
  • CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas
  • CD30 acts as a costimulatory molecule in thymic negative selection
  • In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
  • In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor
  • Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response
  • TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB
  • CD30 is a positive regulator of apoptosis, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity
  • Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
  • CD30 is expressed by mononuclear cells in Hodgkin′s lymphoma, Reed Sternberg cells and most Anaplastic Large Cell Lymphomas (ALCL)
  • CD30 is also expressed by embryonal carcinomas.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0249

--


Antigen:
TNFRSF8

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFRSF8

Gene Alias:
CD30, D1S166E, Ki-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2H2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P28908

Gene Symbols:
TNFRSF8

Immunogen:
Human recombit protein fragment corresponding to amino acids 408-595 of human TNFRSF8 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0251

--


Antigen:
MYL1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MYL1

Gene Alias:
MLC1F, MLC3F

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4632

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1D9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P05976

Gene Symbols:
MYL1

Immunogen:
Human recombit protein fragment corresponding to amino acids 2-150 of human MYL1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0252

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Antigen:
TNFAIP8

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFAIP8

Gene Alias:
GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25816

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95379

Gene Symbols:
TNFAIP8

Immunogen:
Full length human recombit protein of human TNFAIP8 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0253

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Antigen:
GRHL3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GRHL3

Gene Alias:
SOM, TFCP2L4, VWS2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57822

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5F3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8TE85

Gene Symbols:
GRHL3

Immunogen:
Full length human recombit protein of human GRHL3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1