50-167-0633

BRCC3 Mouse anti-Human, Clone: OTI6G7, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-0633-Each-of-1 In Stock ₹ 58,009.68

50-167-0633 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

BRCC3

Classification

Monoclonal

Conjugate

Unconjugated

Gene

BRCC3

Gene Alias

BRCC36, C6.1A, CXorf53

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79184

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI6G7

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P46736

Gene Symbols

BRCC3

Immunogen

Human recombit protein fragment corresponding to amino acids 41-316 of human BRCC3 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Together with the breast and ovarian predisposition proteins BRCA1 and BRCA2 and RAD51 and BRCC45, BRCC36 forms a holoenzyme complex that possesses a ubiquitin E3 ligase activity
  • Aberrant levels of BRCC36 were detected in sporadic breast tumors and depletion of either BRCC36 or BRCC45 by siRNA resulted in increased sensitivity to ionizing radiation and defects in the G2/M checkpoint, indicating that BRCC36 acts to enhance cellular survival following DNA damage
  • Recent experiments have shown that BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation, suggesting that BRCC36 may be an important target in the treatment of radiation-resistant breast tumors
  • At least two isoforms of BRCC36 are known to exist.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0633

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Antigen:
BRCC3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BRCC3

Gene Alias:
BRCC36, C6.1A, CXorf53

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79184

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6G7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P46736

Gene Symbols:
BRCC3

Immunogen:
Human recombit protein fragment corresponding to amino acids 41-316 of human BRCC3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0635

--


Antigen:
HS1BP3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HS1BP3

Gene Alias:
ETM2, HS1-BP3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64342

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI10D9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q53T59

Gene Symbols:
HS1BP3

Immunogen:
Human recombit protein fragment corresponding to amino acids 145-392 of human HS1BP3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-167-0638

--


Antigen:
FAM54A

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MTFR2

Gene Alias:
DUFD1, FAM54A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100911069, 113115, 483997

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2G8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
B0K035, Q6P444

Gene Symbols:
MTFR2

Immunogen:
Full length human recombit protein of human FAM54A produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0639

--


Antigen:
THAP8

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
THAP8

Gene Alias:
THAP domain containing 8

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
199745

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2A1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8NA92

Gene Symbols:
THAP8

Immunogen:
Human recombit protein fragment corresponding to amino acids 86-274 of human THAP8 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1