50-167-0821

PDPN Mouse anti-Human, Clone: OTI7B4, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-0821-Each-of-1 In Stock ₹ 58,009.68

50-167-0821 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

PDPN

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PDPN

Gene Alias

AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10630

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI7B4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q86YL7

Gene Symbols

PDPN

Immunogen

Human recombit protein fragment corresponding to amino acids 23-131 of human PDPN produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight
  • Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs
  • Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells
  • As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes
  • Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential
  • Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue
  • Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells
  • Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC
  • Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm
  • Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0821

--


Antigen:
PDPN

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10630

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI7B4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q86YL7

Gene Symbols:
PDPN

Immunogen:
Human recombit protein fragment corresponding to amino acids 23-131 of human PDPN produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0822

--


Antigen:
GPR17

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GPR17

Gene Alias:
G protein-coupled receptor 17

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2840

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI10B8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q13304

Gene Symbols:
GPR17

Immunogen:
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GPR17 C-terminal. The exact sequence is proprietary.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0824

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Antigen:
GPR26

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GPR26

Gene Alias:
G protein-coupled receptor 26

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
192153, 233919, 2849

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3D10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8BZA7, Q8NDV2, Q9QXI3

Gene Symbols:
Gpr26

Immunogen:
Synthetic peptide

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-167-0826

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Antigen:
RWDD3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RWDD3

Gene Alias:
RSUME

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25950

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI8B3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9Y3V2

Gene Symbols:
RWDD3

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-267 of human RWDD3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a