50-167-0973

NEDD4 Mouse anti-Human, Clone: OTI7A1, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-0973-Each-of-1 In Stock ₹ 58,009.68

50-167-0973 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

NEDD4

Classification

Monoclonal

Conjugate

Unconjugated

Gene

NEDD4

Gene Alias

NEDD4-1, RPF1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4734

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI7A1

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P46934

Gene Symbols

NEDD4

Immunogen

Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
  • It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
  • It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
  • It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
  • It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
  • NEDD4 protein is localized to the sarcolemmal region of muscle fibers
  • Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
  • Hence it acts as down regulator of Notch-1 gene expression.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0973

--


Antigen:
NEDD4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NEDD4

Gene Alias:
NEDD4-1, RPF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4734

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI7A1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P46934

Gene Symbols:
NEDD4

Immunogen:
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-167-0974

--


Antigen:
MTHFR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MTHFR

Gene Alias:
methylenetetrahydrofolate reductase

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4524

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4C5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P42898

Gene Symbols:
MTHFR

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-230 of human MTHFR produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0975

--


Antigen:
MMP11

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MMP11

Gene Alias:
SL-3, ST3, STMY3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4320

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2D7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P24347

Gene Symbols:
MMP11

Immunogen:
Human recombit protein fragment corresponding to amino acids 239-488 of human MMP11 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0976

--


Antigen:
ZNF480

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ZNF480

Gene Alias:
zinc finger protein 480

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
147657

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2G2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8WV37

Gene Symbols:
ZNF480

Immunogen:
Full length human recombit protein of human ZNF480 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1