50-167-1223

IDH1 (mutant R132H) Rat anti-Human, Clone: OTI3E12, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-1223-Each-of-1 In Stock ₹ 43,217.21

50-167-1223 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

IDH1 (mutant R132H)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O75874

Gene Symbols

IDH1

Immunogen

Synthetic peptide around the R132H mutation region of the human IDH conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

Western Blot

Clone

OTI3E12

Conjugate

Unconjugated

Gene

IDH1

Gene Alias

IDH1-mutant

Host Species

Rat

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3417

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Isocitrate dehydrogenases such as IDH1 catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate
  • These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+)
  • Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predomitly cytosolic
  • Each NADP(+)-dependent isozyme is a homodimer
  • The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes
  • It contains the PTS-1 peroxisomal targeting signal sequence
  • The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid
  • The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production
  • This product is specific for IDH1 (mutant R132H).

Compare Similar Items

Show Difference

Img

OriGene

50-167-1223

--


Antigen:
IDH1 (mutant R132H)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75874

Gene Symbols:
IDH1

Immunogen:
Synthetic peptide around the R132H mutation region of the human IDH conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Western Blot

Clone:
OTI3E12

Conjugate:
Unconjugated

Gene:
IDH1

Gene Alias:
IDH1-mutant

Host Species:
Rat

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3417

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-1233

--


Antigen:
IdU

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Iododeoxyuridine coupled to keyhole limpet hemocyanin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
OTI7C9

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
IdU

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-1234

--


Antigen:
IdU

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Iododeoxyuridine coupled to keyhole limpet hemocyanin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
OTI2B10

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
IdU

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-1236

--


Antigen:
BrdU

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Bromodeoxyuridine coupled to keyhole limpet hemocyanin (KLH).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
OTI2G6

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
BrdU; 5-Bromo-2-deoxyuridine; Bromodeoxyuridine

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid